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abr. 2006
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| _version_ | 1869362456218828810 |
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| building | Biblioteca Facultad de Medicina |
| format | Book |
| fullrecord | oai:netcat:be-dblil-71
BR1.1
LILACS
LILACSEXPRESS
MEDLINE
S
as
Internet
<i>http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400010&lng=pt&nrm=iso&tlng=es</i>
Cirrosis biliar primaria: experiencia de trece años en dos centros de referencia
Primary biliary cirrhosis: a thirteen years experience
Rev. mÚd. Chile
134
4
0034-9887
tab
Es
En
abr. 2006
20060400
19
Background: Primary biliary cirrhosis (PBC) is a chronic cholestatic disease, which can progress to hepatic failure. Aim: To study the clinical presentation, pathological features, treatment and outcome of a group of patients with PBC. Material and methods: Retrospective review of medical records of 115 patients (110 females, age range 30-76 years) with PBC. Clinical presentation, pathological stage, treatment, outcome and eventual use of liver transplantation, were recorded. Result: Seventy eight percent of patients were symptomatic at presentation (itching in 69% and malaise in 62%). Antimitochondrial antibodies were positive in 56%. No clinical or laboratory differences were observed between symptomatic patients or those with positive antimitochondrial antibodies and the rest of the study group. Sjõgren syndrome was present in 38%, hypothyroidism in 13%, scleroderma in 7% and rheumatoid arthritis in 5%. Initially, 61% had fibrosis and/or cirrhosis, and ursodeoxycholic acid was indicated in 94% of the patients. Fifteen patients underwent liver transplantation due to upper digestive bleeding or itching. Survival has been 67% at 36 months after transplantation. In one transplanted liver, PBC recurred. Conclusions: An early diagnosis and treatment of a progressive disease such as PBC will reduce the incidence of complications and the use of costly treatments. (AU)
2006-06-09
20060609
SCIELO
JA
FONTE
428547
<d>BIREME_LXP</d>
<s>S0034-98872006000400010</s>
Valera M., JosÚ Miguel
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Smok S., Gladys
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>AnatomÝa Patológica</s3>
<c>Santiago</c>
<p>Chile</p>
Poniachik T., Jaime
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Oksenberg R., Danny
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Silva P., Guillermo
<s1>ClÝnica Las Condes</s1>
<s2>Departamento de GastroenterologÝa</s2>
<c>Santiago</c>
<p>Chile</p>
Ferrario B., Mario
<s1>ClÝnica Las Condes</s1>
<s2>Unidad de Trasplante Hepßtico</s2>
<c>Santiago</c>
<p>Chile</p>
Buckel G., Erwin
<s1>ClÝnica Las Condes</s1>
<s2>Unidad de Trasplante Hepßtico</s2>
<c>Santiago</c>
<p>Chile</p>
Brahm B., Javier
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
<f>469</f>
<l>474</l>
71
|
| id | oai:netcat:be-dblil-71 |
| institution | UMSS |
| publishDate | abr. 2006 |
| record_format | abcd |
| spellingShingle | Registro ABCD - ID: oai:netcat:be-dblil-71 |
| title | Registro ABCD - ID: oai:netcat:be-dblil-71 |
| url | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400010&lng=pt&nrm=iso&tlng=es |