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BR1.1
LILACS
LILACSEXPRESS
MEDLINE
S
as
Internet
<i>http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400001&lng=pt&nrm=iso&tlng=es</i>
Función pancreßtica exocrina en diabetes mellitus: Determinación de elastasa fecal
Pancreatic exocrine function in diabetes mellitus: Determination of fecal elastase
Rev. mÚd. Chile
134
4
0034-9887
ilus
tab
Es
En
abr. 2006
20060400
21
Background: One of the complications of diabetes mellitus is the development of pancreatic exocrine insufficiency. Aim: To study pancreatic exocrine function in diabetics patients. Material and methods: Seventy two diabetic patients were included in the protocol, but two were withdrawn because an abdominal CAT scan showed a chronic calcified pancreatitis, previously undiagnosed. Fecal elastase was measured by ELISA and the presence of fat in feces was assessed using the steatocrit. Results: Mean age was 60±12 years and 67 (96%) patients had a type 2 diabetes. Fecal elastase was normal (elastase >200 Ág/g) in 47 (67%) patients, mildly decreased (100-200 Ág/g) in 10 (14%) and severely decreased in 13 (19%). There was a significant association between elastase levels and time of evolution of diabetes (p=0.049) and between lower elastase levels and the presence of a positive steatocrit (p=0.042). No significant association was found between elastase levels and other chronic complications of diabetes such as retinopathy, nephropathy, neuropathy, microangiopathy or with insulin requirement. Conclusions: One third of this group of diabetic patients had decreased levels of fecal elastase, that was associated with the time of evolution of diabetes. Patients with lower levels of elastase have significantly more steatorrhea. Among diabetics it is possible to find a group of patients with non diagnosed chronic pancreatitis.(AU)
2006-06-09
20060609
SCIELO
JA
FONTE
428538
<d>BIREME_LXP</d>
<s>S0034-98872006000400001</s>
Mancilla A., Carla
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Departamento de Medicina. Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Hurtado H., Carmen
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Departamento de Medicina. Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Tobar A., Eduardo
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Unidad de Paciente CrÝtico. Intermedio MÚdico</s3>
<c>Santiago</c>
<p>Chile</p>
Orellana N., Ivonne
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Departamento de Medicina. Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Pineda B., Pedro
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Departamento de Medicina. Sección de EndocrinologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Castillo M., Ivßn
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Departamento de Medicina. Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
Ledezma R., Rodrigo
<s1>Universidad de Chile</s1>
<s2>Hospital ClÝnico</s2>
<s3>Departamento de Medicina. Sección de GastroenterologÝa</s3>
<c>Santiago</c>
<p>Chile</p>
<f>407</f>
<l>414</l>
80
|
| id | oai:netcat:be-dblil-80 |
| institution | UMSS |
| publishDate | abr. 2006 |
| record_format | abcd |
| spellingShingle | Registro ABCD - ID: oai:netcat:be-dblil-80 |
| title | Registro ABCD - ID: oai:netcat:be-dblil-80 |
| url | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400001&lng=pt&nrm=iso&tlng=es |